Hydrogen Bromide → Phenol, 4-(3-pyridinyl)-

HRID 1600959Notes

Reaction equation

HRID 1600959 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=2)=[CH:5][CH:4]=1.Br>C(O)(=O)C>[OH:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=2)=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 41331923-(4-methoxyphenyl)pyridine

Product 1

HCID 153040Phenol, 4-(3-pyridinyl)-Yield 72.7%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Prepared according to the method as described in Example 33b) from 3-(4-methoxyphenyl)pyridine (2.5 g), 48% aqueous hydrobromic acid (25 ml) and acetic acid (25 ml) to give the sub-title compound as a pale orange solid (1.68 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-4560ce35498543739792f4b7e7a355b1
Source dataset
uspto-grants-1999_11
Patent number
US05977105

Reaction notes

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