(1,1'-Biphenyl)-2-ol → HCID 21830695, compound

Participants

Reaction Steps

Prepared according to the method described in Example 24b) from (±)-α-(chloromethyl)-3-pyridinepropanol (1.0 g, Example 24a), 2-phenylphenol (0.92 g), ethanol (45 ml) and aqueous sodium hydroxide (1.0 M, 5 ml) with heating at reflux for 1 hour. After work up the residue was purified by column chromatography over silica eluting with hexane:acetone (2:1) to give the title compound as a colourless oil (0.60 g).

Provenance & Evidence