HCID 15885172, compound → HCID 15885173, compound

Participants

Reaction Steps

A solution of 7-nitro-2-trifluoroacetoxy-1,2,3,4-tetrahydroisoquinoline (Stokker, Tetrahedron Letts., 1996, 37, 5453; 3.64 g, 13.3 mmol) in 100 mL EtOH at room temperature was was purged with argon and 10% palladium on carbon (300 mg) added. The mixture was then stirred under an atmosphere of hydrogen gas for 2 h. then filtered and the solvent removed in vacuo to yield a white solid which was sufficiently pure for use in the next step.

Provenance & Evidence