Phenylboronic Acid → HCID 18394396, compound

HRID 1601033Notes

Reaction equation

[C:1]([N:8]1[C@H:17]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH2:16][C:15]2[C:10](=[CH:11][C:12](OS(C(F)(F)F)(=O)=O)=[CH:13][CH:14]=2)[CH2:9]1)([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].[C:31]1(B(O)O)[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[C:1]([N:8]1[C@H:17]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH2:16][C:15]2[C:10](=[CH:11][C:12]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)=[CH:13][CH:14]=2)[CH2:9]1)([O:3][C:4]([CH3:5])([CH3:7])[CH3:6])=[O:2]

Participants

Reactant 2

HCID 66827Phenylboronic Acid

HCID 18394397HCID 18394397, compound

Product 1

HCID 18394396HCID 18394396, compound

Procedure

The triflate from Step 2 was coupled with phenyl boronic acid following the procedure of Example 11 to give the title compound as an oil.

Sources & evidence

ORD record: ord-b5911c592a984803ba4808626574f661
Source dataset: uspto-grants-1999_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05977134

Reaction notes

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