HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1601072Generated: October 29, 2026
Methylamine → N,1-dimethylindole-2-carboxamide
https://huagongshe.com/reaction/1601072
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | ethyl 1-methyl-1H-indole-2-carboxylate | HCID 143368 | — |
| Product | N,1-dimethylindole-2-carboxamide | HCID 12303315 | — |
Reaction Steps
A mixture of ethyl 1-methylindole-2-carboxylate (4.06 g, 20 mmol) and methylamine (50 mL) was heated at 80° C. in a sealed glass vessel overnight. The reaction was cooled and the title compound (2.4 g, 64%) was collected by filtration as a colorless solid. MS (ES) m/e 189.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05977101 |
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| Source dataset | uspto-grants-1999_11 |
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| ORD ID | ord-7f668896825c467f9ea44a3a0d7776ab |
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| Source note | uspto-grants-1999_11 |
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