反应详情

温度

80 °C

A mixture of ethyl 1-methylindole-2-carboxylate (4.06 g, 20 mmol) and methylamine (50 mL) was heated at 80° C. in a sealed glass vessel overnight. The reaction was cooled and the title compound (2.4 g, 64%) was collected by filtration as a colorless solid. MS (ES) m/e 189.0 (M+H)+.

1. temperatureThe reaction was cooled
2. filtrationthe title compound (2.4 g, 64%) was collected by filtration as a colorless solid