HCID 737463, compound → HCID 9913721, compound

HRID 1601121Notes

Reaction equation

HRID 1601121 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][C@@H:12]([CH3:16])[C:13]([OH:15])=[O:14])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[Na].Cl.Cl.[CH3:20][O:21][C:22]1[CH:27]=[CH:26][C:25]([N:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)=[CH:24][CH:23]=1>>[CH3:20][O:21][C:22]1[CH:23]=[CH:24][C:25]([N:28]2[CH2:33][CH2:32][N:31]([C:2]3[CH:7]=[CH:6][C:5]([S:8]([NH:11][C@@H:12]([CH2:16][C:2]4[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=4)[C:13]([OH:15])=[O:14])(=[O:10])=[O:9])=[CH:4][CH:3]=3)[CH2:30][CH2:29]2)=[CH:26][CH:27]=1

Participants

4

Reactant 3

HCID 737463HCID 737463, compoundHCID 27237001-(4-Methoxyphenyl)-piperazine, dihydrochlorideHCID 5360545Sodium

Product 1

HCID 9913721HCID 9913721, compound

Procedure

In a manner similar to Example 3(b), (S)-2-(4-fluoro-benzenesulfonylamino}-propionic acid, sodium salt and 4-(4-methoxy-phenyl)-piperazine dihydrochloride were condensed to give the title compound as a brown solid, mp=203-205° C.

Workup

  1. customcondensed

Sources & evidence

ORD record
ord-7de8a9c1ce1c4665a5f4b101989717d1
Source dataset
uspto-grants-1999_11
Patent number
US05977141

Reaction notes

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