反应详情

One hundred (100) grams of rutin was dissolved in one (1) liter of lN hydrochloric acid at a temperature of 80-90° C., and allowed to react at that temperature for a total of 3 hours, forming a yellowish-brown precipitate. The resultant mixture was allowed to cool to room temperature and the precipitate removed by filtration, with continual washing with distilled water, until a pH of 6.0-6.5 was obtained. The precipitate was dried and redissolved in 90% ethyl alcohol, and filtered to remove impurities, with the alcohol subsequently distilled off. The remaining precipitate was then suspended in 200 ml of distilled water. Gradually, a solution of lN sodium hydroxide was added, until a clear, golden-brown solution without a precipitate was obtained. This solution was oven dried at a temperature of 70-80° C., yielding a brown powder of quercetin chalcone. The quercetin chalcone produced by this method was soluble in distilled water, a concentration of 20% quercetin chalcone in water was readily produced. Quercetin, on the other hand, was almost totally insoluble in water.

1. customto react at that temperature for a total of 3 hours
2. customforming a yellowish-brown precipitate
3. customthe precipitate removed by filtration
4. washwith continual washing with distilled water, until a pH of 6.0-6.5
5. customwas obtained
6. customThe precipitate was dried
7. dissolutionredissolved in 90% ethyl alcohol
8. filtrationfiltered
9. customto remove impurities
10. distillationwith the alcohol subsequently distilled off
11. additionGradually, a solution of lN sodium hydroxide was added
12. customuntil a clear, golden-brown solution without a precipitate was obtained
13. customdried at a temperature of 70-80° C.