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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1601644Generated: October 30, 2026

p-Bromoacetophenone → 4'-Piperidinoacetophenone

https://huagongshe.com/reaction/1601644

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-BromoacetophenoneHCID 7466—
ReactantPiperidineHCID 8082—
Product4'-PiperidinoacetophenoneHCID 82561—

Reaction Steps

without solvents (e.g. B. G. Kresze and H. Goetz, Chern. Berichte 90, 2161, 2174 (1957)), reaction of p-bromoacetophenone with piperidine under reflux with 19% yields of 1-(4-piperidinophenyl)ethanone; or

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05977357
Source datasetuspto-grants-1999_11
ORD IDord-c7d294b0d9d0460286571eac7c799da9
Source noteuspto-grants-1999_11