HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 21832300, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 2,6-Difluorobenzoyl chloride | HCID 87438 | — |
| Reactant | 3-[4-(Trifluoromethoxy)phenoxy]propan-1-amine | HCID 21832289 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 21832300 | HCID 21832300 | — |
Reaction Steps
A tetrahydrofuran (5 ml) solution of 2,6-difluorobenzoyl chloride (0.88 g) was added dropwise under ice-cooling and stirring to a tetrahydrofuran (20 ml) solution of 3-(4-trifluoromethoxyphenoxy)propylamine (1.18 g) and triethylamine (0.50 g) and the mixture was further stirred at room temperature for one hour.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977410 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-941f3bec288a492a93808c7a05436b7f |
| Source note | uspto-grants-1999_11 |