Sulfuric Acid → HCID 19609787, compound

Participants

Reaction Steps

A mixed solution of acetic anhydride (15 ml), 1-(4-trifluoromethoxyphenyl)-5-(4-cyano-2,5-difluoroanilino)tetrazole (1.5 g) and concentrated sulfuric acid (1 ml) was stirred at 70 to 80° C. for 1 hour. After unreacted acetic anhydride was distilled off under reduced pressure, the residue was washed with water and n-hexane to obtain 1-(4-trifluoromethoxyphenyl)-5-(4-cyano-2,5-difluoro-N-acetylanilino)tetrazole (1.55 g).

Provenance & Evidence