Formic Acid → HCID 178489914, compound

Participants

Reaction Steps

A mixture of 2.55 g (8.38 mmol) of 5-amino-1-benzyl-4-cyano-3-(3-methoxy-phenyl)-pyrazole and 20 ml of 85% aqueous formic acid is heated under reflux for 21 hours and then cooled to room temperature and, with stirring, a small amount of water is added thereto. Filtering and washing the filter residue with water yield the title compound; m.p. 183-185° C.; FAB-MS: (M+H)+ =333.

Provenance & Evidence