Ethanol → HCID 1704466, compound

HRID 1602295Notes

Reaction equation

HRID 1602295 reaction equation
CS[C:3]([S:9][CH3:10])=[C:4]([C:7]#[N:8])[C:5]#[N:6].[CH2:11]([O:13][C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][CH:15]=1)[CH3:12].C(O)C>C(OCC)C>[C:5]([C:4](=[C:3]([NH:18][C:17]1[CH:19]=[CH:20][C:14]([O:13][CH2:11][CH3:12])=[CH:15][CH:16]=1)[S:9][CH3:10])[C:7]#[N:8])#[N:6]

Participants

5

Reactant 3

HCID 702EthanolHCID 90764-EthoxyanilineHCID 992292-(Bis(methylsulfanyl)methylidene)propanedinitrile

Product 1

HCID 1704466HCID 1704466, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Conditions

Temperature
0 °C

Procedure

A mixture of 17.03 g (0.1 mol) of 3,3-bis-methylmercapto-2-cyano-acrylonitrile, 12.94 ml (0.1 mol) of 4-ethoxy-aniline and 60 ml of ethanol is heated under reflux for 2 hours. Then, with stirring, 120 ml of diethyl ether are added dropwise to the reaction mixture, which is at approx. 30° C. The reaction mixture is then cooled to 0° C. The title compound precipitates in the form of colorless crystals and is filtered off, washed with diethyl ether and dried under a HV; m.p. 141-142° C.

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 2 hours
  3. customis at approx. 30° C
  4. customThe title compound precipitates in the form of colorless crystals
  5. filtrationis filtered off
  6. washwashed with diethyl ether
  7. customdried under a HV

Sources & evidence

ORD record
ord-12f7ecb29f9a44db9cc4f43b8df50fd4
Source dataset
uspto-grants-1999_11
Patent number
US05981533

Reaction notes

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