HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178419339, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4,4'-Dibromobenzil | HCID 96430 | — |
| Reactant | 1-(1H-benzimidazol-2-yl)guanidine | HCID 178512594 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178419339 | HCID 178419339 | — |
Reaction Steps
Following the procedure of Example 1, 4,4'-dibromobenzil (4.42 g, 12 mmol) and 2-guanidinobenzimidazole (1.75 g, 10 mmol) in methanol (100 mL) was treated with a solution of sodium hydroxide (400 mg, 10 mmol) in 10 mL of water. The title compound was isolated as pale yellow crystals (800 mg, 24% yield). mp: 274-278 ° C. (dec); MS (ESI) m/z 683 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05981551 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-bcf3c3e075aa49b593d3977e8c5e0d17 |
| Source note | uspto-grants-1999_11 |