HCID 10198333, compound → HCID 19611642, compound

HRID 1602421Notes

Reaction equation

HRID 1602421 reaction equation
C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.[Pb+4].[O:18]1[C:22]2[CH:23]=[CH:24][CH:25]=[C:26]([CH2:27][CH2:28][CH2:29][NH:30][C:31](=[O:33])[CH3:32])[C:21]=2[CH2:20][CH2:19]1>C(O)(=O)C>[O:18]1[C:22]2[CH:23]=[CH:24][CH:25]=[C:26]([CH2:27][CH2:28][CH2:29][NH:30][C:31](=[O:33])[CH3:32])[C:21]=2[CH:20]=[CH:19]1

Participants

4

Reactant 2

HCID 10198333HCID 10198333, compoundHCID 178418268HCID 178418268, compound

Product 1

HCID 19611642HCID 19611642, compoundYield 41.4%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Lead tetraacetate (210 mg) was added to a solution of N-[3-(2,3-dihydro-benzofuran-4-yl)-propyl]-acetamide (100 mg) in acetic acid (1.5 ml) at 100. The mixture was stirred at room temperature for 2h and at 50° for 16 h. The solvent was evaporated and the residue purified by chromatography to give the title compound as an oil (41 mg).

Workup

  1. customThe solvent was evaporated
  2. customthe residue purified by chromatography

Sources & evidence

ORD record
ord-5728706b3e8a45c19f8e43f00fcc82ec
Source dataset
uspto-grants-1999_11
Patent number
US05981572

Reaction notes

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