Sodium Methoxide → HCID 54079273, compound

HRID 1602707Notes

Reaction equation

HRID 1602707 reaction equation
C[O-].[Na+].[CH3:4][C:5]1[C:6]([C:19]([CH2:21][O:22][C:23]2[CH:24]=[C:25]([CH:30]=[CH:31][C:32]=2[I:33])[C:26]([O:28][CH3:29])=[O:27])=O)=[CH:7][C:8]2[C:9]([CH3:18])([CH3:17])[CH2:10][CH2:11][C:12]([CH3:16])([CH3:15])[C:13]=2[CH:14]=1.[Br-].[CH3:35]P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>C1COCC1>[I:33][C:32]1[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][C:23]=1[O:22][CH:21]=[C:19]([C:6]1[C:5]([CH3:4])=[CH:14][C:13]2[C:12]([CH3:15])([CH3:16])[CH2:11][CH2:10][C:9]([CH3:17])([CH3:18])[C:8]=2[CH:7]=1)[CH3:35]

Participants

5

Reactant 3

HCID 10942334Sodium MethoxideHCID 19612290HCID 19612290, compoundHCID 178503020HCID 178503020, compound

Product 1

HCID 54079273HCID 54079273, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Sodium methoxide (0.62 ml, 3.17 mmol) is added over 8 hours to a mixture of methyl 3-(3-methyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthoyl-methyloxy)-4-iodobenzoate (1.6 g, 3.1 mmol) and methyltriphenylphosphine bromide (1.51 g, 4.2 mmol) in THF (15 ml).

Sources & evidence

ORD record
ord-a22baea061ce4e8e8b4d5cd34091833e
Source dataset
uspto-grants-1999_11
Patent number
US05981776

Reaction notes

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