Thiirane → HCID 19607262, compound

HRID 1602729Notes

Reaction equation

HRID 1602729 reaction equation
[CH3:1][CH:2]1[O:7][CH:6]([CH3:8])[CH2:5][NH:4][CH2:3]1.[S:9]1[CH2:11][CH2:10]1>C1(C)C=CC=CC=1>[CH3:8][CH:6]1[O:7][CH:2]([CH3:1])[CH2:3][N:4]([CH2:11][CH2:10][SH:9])[CH2:5]1

Participants

4

Reactant 2

HCID 9865ThiiraneHCID 1108622,6-Dimethylmorpholine

Product 1

HCID 19607262HCID 19607262, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In a 500 ml three necked flask 115.2 g (1 mol) 2,6-dimethylmorpholine in 250 ml of toluene is heated at 90° C. Then 60.12 g (1 mol) thiirane is added to the resulting reaction mixture dropwise and the reaction mixture is heated for 5 hours under reflux. The reaction mixture is concentrated in vacuum with a rotary evaporator and is fractionally distilled using a Vigreux column.

Workup

  1. temperaturethe reaction mixture is heated for 5 hours
  2. temperatureunder reflux
  3. concentrationThe reaction mixture is concentrated in vacuum with a rotary evaporator
  4. distillationis fractionally distilled

Sources & evidence

ORD record
ord-c8baa796fadf4c5daf774c897dfea1a4
Source dataset
uspto-grants-1999_11
Patent number
US05985253

Reaction notes

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