Hydrochloric Acid → HCID 67578298, compound

HRID 1602936Notes

Reaction equation

HRID 1602936 reaction equation
[CH2:1]([C:5]1[C:14](=[O:15])[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][C:12]=2[S:16][CH3:17])[NH:7][C:6]=1[C:18]([O:20]CC)=[O:19])[CH2:2][CH2:3][CH3:4].[OH-].[Na+].[ClH:25]>O>[ClH:25].[CH2:1]([C:5]1[C:14](=[O:15])[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][C:12]=2[S:16][CH3:17])[NH:7][C:6]=1[C:18]([OH:20])=[O:19])[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 19595378HCID 19595378, compound

Product 1

HCID 67578298HCID 67578298, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.63 g of the product of Step B in 10 ml of a N sodium hydroxide solution was stirred for 2 hours at reflux and the mixture was poured into ice-cooled water, acidified with concentrated hydrochloric acid, separated, washed with water, dried and impasted in 100 ml of ethyl acetate to obtain 495 mg of the desired product melting at 240° C.

Workup

  1. temperatureat reflux
  2. additionthe mixture was poured into ice-
  3. customseparated
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-7adcf8afe6f64748a05e9576b7295553
Source dataset
uspto-grants-1999_11
Patent number
US05985894

Reaction notes

Loading…