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HRID1602946

反应详情

EQUATION

反应方程式

HRID 1602946 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1ccc(N)cc1
HCID12082

Benzoic acid, 4-amino-, methyl ester

C8H9NO2

结构：CCCCC(C(=O)OCC)C(=O)C(=O)OCC
HCID251159

diethyl 2-butyl-3-oxobutanedioate

C12H20O5

PRODUCTS

生成物

1
结构：CCCCC(C(=O)OCC)=C(Nc1ccc(C(=O)OC)cc1)C(=O)OCC
HCID67577966

未命名化合物

收率 100.8%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCC.CCOC(C)=O
溶剂HCID21226206

未命名化合物

CONDITIONS

反应条件

温度
60 °C

PROCEDURE

实验过程

27.8 g of methyl 4-aminobenzoate and 47 g of diethyl 2-butyl-3-oxo-butanedioate were mixed and 2 g of activated siliporite were added. The mixture was stirred for about 30 hours at 60° C. and after chromatography (eluant: hexane-ethyl acetate 95-5), 70 g of the expected product were obtained.

WORKUP

后处理

  1. addition2 g of activated siliporite were added