Methylamine → HCID 154041611, compound

HRID 1603162Notes

Reaction equation

HRID 1603162 reaction equation
[CH3:1][C:2](=[N:26][O:27][CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[C:35](=[N:40][O:41][CH3:42])[C:36](OC)=[O:37])/[C:3](=[N:22]/[O:23][CH2:24][CH3:25])/[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([F:21])([F:20])[F:19])[CH:13]=2)=[CH:6][CH:5]=1.[CH3:43][NH2:44]>C(O)C>[CH3:43][NH:44][C:36](=[O:37])[C:35]([C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=1[CH2:28][O:27][N:26]=[C:2]([CH3:1])/[C:3](=[N:22]/[O:23][CH2:24][CH3:25])/[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([F:20])([F:21])[F:19])[CH:13]=2)=[CH:6][CH:5]=1)=[N:40][O:41][CH3:42]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 154041612HCID 154041612, compound

Product 1

HCID 154041611HCID 154041611, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 6.8 g of methyl 2-[[[(1-methyl-2-(4-(3-trifluoromethylphenylmethoxy)-phenyl)-2-E-[ethoxyimino]ethylidene)amino]oxy]methyl]-α-(methoxyimino)-phenylacetate and 4.3 ml of an 8 molar solution of methylamine in ethanol is left to stand at room temperature for 4 days. The mixture is then evaporated in vacuo. The residue is taken up in methyl acetate and the solution is washed with water and saturated sodium chloride solution, dried over sodium sulfate and evaporated in vacuo. The residue is recrystallized from methyl acetate/hexane 1:1. The title compound with a melting point of 130-132° C. is obtained.

Workup

  1. waitis left
  2. customThe mixture is then evaporated in vacuo
  3. washthe solution is washed with water and saturated sodium chloride solution
  4. dry with materialdried over sodium sulfate
  5. customevaporated in vacuo
  6. customThe residue is recrystallized from methyl acetate/hexane 1:1

Sources & evidence

ORD record
ord-37831c2cd6424355a1d0888a6c3e97cb
Source dataset
uspto-grants-1999_11
Patent number
US05985921

Reaction notes

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