HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acrylate → 1-Pyrrolidinepropionic acid, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Pyrrolidinepropionic acid, ethyl ester | HCID 80590 | — |
Reaction Steps
Ethyl acrylate (110.0 g; 1.1 mol) was dissolved in THF (250 ml). To this a solution of pyrrolidine (71.5 g; 1.0 mol) in THF (100 ml) was added dropwise in 75 minutes, after which stirring was continued for 3.5 hours at room temperature. The reaction mixture was evaporated by means of a rotary evaporator. The yield was 161.8 g (94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05986029 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-beb027b3e00248df94c4c0355c105d2d |
| Source note | uspto-grants-1999_11 |