m-Chloroperbenzoic acid → HCID 19609114, compound

HRID 1603209Notes

Reaction equation

HRID 1603209 reaction equation
[Cl:1][C:2]1[C:3]([CH2:11][N:12]2[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:15]([S:22][CH3:23])[N:14]=[C:13]2[CH2:24][CH2:25][CH3:26])=[CH:4][C:5]2[O:9][CH2:8][O:7][C:6]=2[CH:10]=1.ClC1C=CC=C(C(OO)=[O:35])C=1>C(Cl)Cl>[Cl:1][C:2]1[C:3]([CH2:11][N:12]2[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:15]([S:22]([CH3:23])=[O:35])[N:14]=[C:13]2[CH2:24][CH2:25][CH3:26])=[CH:4][C:5]2[O:9][CH2:8][O:7][C:6]=2[CH:10]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 54272883HCID 54272883, compound

Product 1

HCID 19609114HCID 19609114, compoundYield 91.3%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

9.26 g of the product obtained in Stage 4 above is introduced into 400 ml of methylene chloride at 0° C. and 5.8 g of metachloroperbenzoic acid is added. Agitation is carried out for one hour at ambient temperature and the reaction medium is washed with sodium and potassium hydride, extraction is carried out with methylene chloride, the extracts are washed with water, dried, and the solvent is evaporated off. After chromatography, 8.8 g of expected product is obtained. M.p.=187° C.

Workup

  1. washthe reaction medium is washed with sodium and potassium hydride, extraction
  2. washthe extracts are washed with water
  3. customdried
  4. customthe solvent is evaporated off

Sources & evidence

ORD record
ord-9455eeef810540b7a44b21ee16a99189
Source dataset
uspto-grants-1999_11
Patent number
US05986103

Reaction notes

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