Trifluoroacetic anhydride → HCID 19609113, compound

Participants

Reaction Steps

800 mg of the product obtained in Stage 5 above is introduced into 16 ml of methylene chloride and 0.54 ml of trifluoroacetic anhydride is added. Agitation is carried out for 30 minutes, followed by evaporation to dryness and the residue is taken up in 10 ml of methanol and 4 ml of triethylamine. After agitation for 30 minutes, extraction is carried out with chloroform, the extracts are washed with a saturated solution of ammonium chloride, dried and evaporated to dryness. In this way 720 mg of expected product is obtained.

Provenance & Evidence