HCID 15289126, compound → HCID 15289127, compound

HRID 1603222Notes

Reaction equation

HRID 1603222 reaction equation
[NH2:1][C:2]12[CH2:12][CH2:11][CH:8]([CH:9]=[CH:10]1)[CH:7]1[CH:3]2[CH2:4][N:5](CC2C=CC=CC=2)[CH2:6]1>C(O)C.[Pd]>[NH2:1][C:2]12[CH2:10][CH2:9][CH:8]([CH2:11][CH2:12]1)[CH:7]1[CH:3]2[CH2:4][NH:5][CH2:6]1

Participants

4

Reactant 1

HCID 15289126HCID 15289126, compound

Product 1

HCID 15289127HCID 15289127, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

8.3 g (32.6 mmol) of 1-amino-4-benzyl-4-azatricyclo[5.2.2.02,6 ]undec-8-ene are hydrogenated in 100 ml of ethanol over 1 g of palladium/active charcoal at 100° C./100 bar. The catalyst is filtered off with suction, the filtrate is concentrated and the residue is distilled.

Workup

  1. filtrationThe catalyst is filtered off with suction
  2. concentrationthe filtrate is concentrated
  3. distillationthe residue is distilled

Sources & evidence

ORD record
ord-875da268b75e4473bba70763d2a28d10
Source dataset
uspto-grants-1999_11
Patent number
US05986105

Reaction notes

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