HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Timolol Maleate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Methylbutanoic Acid | HCID 8314 | — |
| Reactant | Timolol | HCID 33624 | — |
| Catalyst | Zinc Acetate | HCID 11192 | — |
| Product | Timolol Maleate | HCID 5281056 | — |
Reaction Steps
15 grams of Carbopol 974P is dispersed in 40 grams of heavy mineral oil USP and is added to 841.5 grams of water containing 2.5 grams of timolol meleate with vigorous stirring. 100 grams of water containing 1.0 gram of zinc acetate is added in a controlled fashion with homogenization to get a particle size distribution size below 5 micron.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05989535 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-9cca235f36404870a5655411ed51d3e0 |
| Source note | uspto-grants-1999_11 |