反应详情

N-(4-methoxybenzyl)-1-hexyl phthalimide (19.9 g, 60 mmol) was dissolved in ethanol (300 ml) and hydrazine monohydrate (8.9 g, 0.11 mol) was added. The mixture was refluxed for 3 hours, filtered, the residue washed with ethanol and the filtrate evaporated. The residue was taken up in diethyl ether, filtered and the residue washed well with ether. Evaporation of the filtrate gave a yellow oil which was purified by distillation to give a clear oil bp 108-110° C., 0.02 mbar.

1. temperatureThe mixture was refluxed for 3 hours
2. filtrationfiltered
3. washthe residue washed with ethanol
4. customthe filtrate evaporated
5. filtrationfiltered
6. washthe residue washed well with ether
7. customEvaporation of the filtrate
8. customgave a yellow oil which
9. distillationwas purified by distillation