Methyl bromoacetate → HCID 54567614, compound

HRID 1603671Notes

Reaction equation

HRID 1603671 reaction equation
[CH3:1][O:2][C:3]1[CH:15]=[CH:14][C:6]([CH2:7][S:8][CH:9]2[NH:12][C:11](=[O:13])[CH2:10]2)=[CH:5][CH:4]=1.Br[CH2:17][C:18]([O:20][CH3:21])=[O:19]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][S:8][CH:9]2[N:12]([CH2:17][C:18]([O:20][CH3:21])=[O:19])[C:11](=[O:13])[CH2:10]2)=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 60984Methyl bromoacetateHCID 19605402HCID 19605402, compound

Product 1

HCID 54567614HCID 54567614, compound

Procedure

Treatment of 4-(4-methoxybenzylthio)-azetidin-2-one (7 g) with methyl bromoacetate (5.3 g) under the conditions described for Example 29a gave the title compound as a colourless solid, m.p. 45-46° C., (5.9 g, 64%)

Sources & evidence

ORD record
ord-b6e92f55d5ea4211a47f995922380f5b
Source dataset
uspto-grants-1999_11
Patent number
US05990102

Reaction notes

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