Hydrazine hydrate (1:1) → HCID 178514362, compound

HRID 1603677Notes

Reaction equation

HRID 1603677 reaction equation
[S:1]=[C:2]1[NH:10][C:9]2[NH:8][CH:7]=[N:6][C:5]=2[C:4](=S)[NH:3]1.O.[NH2:13][NH2:14]>>[NH:13]([C:4]1[C:5]2[N:6]=[CH:7][NH:8][C:9]=2[NH:10][C:2](=[S:1])[N:3]=1)[NH2:14]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 178527910HCID 178527910, compound

Product 1

HCID 178514362HCID 178514362, compoundYield 61%

Conditions

Temperature
120 °C

Procedure

2,6-Dithioxo-1,2,3,6-tetrahydro-9H-purine (0.5 g, 2.7 mmol) was added to 80% hydrazine hydrate (5 ml), and the mixture was stirred with heat for 10 minutes at 120° C. After completion of reaction, crystals that precipitated were collected by filtration, and washed with water. The crystals were recrystallized from water to obtain 0.30 g (yield 61%) of colorless powdery crystals (m.p.=292° C. (decomposed)).

Workup

  1. customAfter completion of reaction, crystals that
  2. customprecipitated
  3. filtrationwere collected by filtration
  4. washwashed with water
  5. customThe crystals were recrystallized from water

Sources & evidence

ORD record
ord-ef2e669f84674c328473b5552871eea4
Source dataset
uspto-grants-1999_11
Patent number
US05990118

Reaction notes

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