4-tert-Butylcatechol → HCID 15289112, compound

HRID 1603689Notes

Reaction equation

HRID 1603689 reaction equation
[C:1]1(=[O:7])[NH:5][C:4](=[O:6])[CH:3]=[CH:2]1.[C:8]1([C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH2:13][CH2:12][CH:11]=[CH:10][CH:9]=1.C(C1C=C(O)C(=CC=1)O)(C)(C)C>C1(C)C=CC=CC=1>[CH2:17]([O:16][C:14]([C:8]12[CH2:13][CH2:12][CH:11]([CH:10]=[CH:9]1)[CH:3]1[CH:2]2[C:1](=[O:7])[NH:5][C:4]1=[O:6])=[O:15])[CH3:18]

Participants

5

Reactant 3

HCID 73814-tert-ButylcatecholHCID 10935MaleimideHCID 110948161,3-Cyclohexadiene-1-carboxylic acid, ethyl ester

Product 1

HCID 15289112HCID 15289112, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

13.5 g (0.138 mol) of maleimide and 25.3 g (0.17 mol) of ethyl 1,3-cyclohexadiene-1-carboxylate are heated under reflux with 1.4 g of 4-(tertbutyl)-pyrocatechol in 275 ml of toluene overnight. The mixture is concentrated and the residue is recrystallized from isopropanol.

Workup

  1. concentrationThe mixture is concentrated
  2. customthe residue is recrystallized from isopropanol

Sources & evidence

ORD record
ord-742f813442094400bd074cecc47a2bbb
Source dataset
uspto-grants-1999_11
Patent number
US05990122

Reaction notes

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