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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1603877Generated: October 30, 2026

Diethyl Oxalate → Ethyl Acetate

https://huagongshe.com/reaction/1603877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl OxalateHCID 7268—
ReactantN-(3-acetyl-2-hydroxyphenyl)-2-(benzyloxymethyl)chromane-6-carboxamideHCID 19606371—
ProductEthyl AcetateHCID 885766%
ProductEthyl 8-[2-(benzyloxymethyl)chromane-6-carboxamido]-4-oxo-4H-1-benzopyran-2-carboxylateHCID 19606281—

Reaction Steps

Following the process described at point A, starting from N-(3-acetyl-2-hydroxyphenyl)-2-(benzyloxymethyl)chromane-6-carboxamide and diethyl oxalate, the title compound was prepared, which was purified by warm crystallization in ethyl acetate (66% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05990142
Source datasetuspto-grants-1999_11
ORD IDord-9f384bd90a66428b87d2d2bab5374246
Source noteuspto-grants-1999_11