HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Oxalate → ethyl 6-bromo-8-nitro-4-oxo-4H-1-benzopyran-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Oxalate | HCID 7268 | — |
| Reactant | 5'-Bromo-2'-hydroxy-3'-nitroacetophenone | HCID 689071 | — |
| Product | ethyl 6-bromo-8-nitro-4-oxo-4H-1-benzopyran-2-carboxylate | HCID 19606344 | 77% |
Reaction Steps
Following the process described in example 1 (point A), starting from 5-bromo-2-hydroxy-3-nitroacetophenone and diethyl oxalate, the title compound was prepared, which was purified by crystallization in tetrahydrofuran:ethanol mixtures (77% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05990142 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-229865d3952146b6b1534cdfe4980eeb |
| Source note | uspto-grants-1999_11 |