Hydrochloric Acid → Hydrochloric Acid

HRID 1603884Notes

Reaction equation

HRID 1603884 reaction equation
[N+:1]([C:4]1[C:13]2[O:12][C:11]([C:14]3[NH:18][N:17]=[N:16][N:15]=3)=[CH:10][C:9](=[O:19])[C:8]=2[CH:7]=[CH:6][CH:5]=1)([O-])=O.C(Cl)(Cl)[Cl:21].Cl>CO.[Pd]>[ClH:21].[NH2:1][C:4]1[C:13]2[O:12][C:11]([C:14]3[NH:18][N:17]=[N:16][N:15]=3)=[CH:10][C:9](=[O:19])[C:8]=2[CH:7]=[CH:6][CH:5]=1

Participants

7

Reactant 3

HCID 313Hydrochloric AcidHCID 6212ChloroformHCID 178515803HCID 178515803, compound

Product 2

HCID 313Hydrochloric AcidHCID 178507421HCID 178507421, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Following the process described in example 1 (point B), by hydrogenating for 4 h 8-nitro-4-oxo-2-(5-1H-tetrazolyl)-4H-1-benzopyran (0.896 g, 3.46 mmol) with 5% palladium-on-charcoal (91 mg) in a mixture of methanol (65 ml), chloroform (20 ml) and concentrated hydrochloric acid (2 ml), the title compound was prepared as its corresponding hydrochloride (quantitative yield).

Sources & evidence

ORD record
ord-af93e6ae767e4b74ab2d17e7c00cb0a3
Source dataset
uspto-grants-1999_11
Patent number
US05990142

Reaction notes

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