HCID 19606307, compound → Methanol

HRID 1603888Notes

Reaction equation

HRID 1603888 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][CH:10]2[CH2:19][CH2:18][C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:20]([OH:22])=O)[CH:16]=3)[O:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:23][C:24]1[C:33]2[O:32][C:31]([C:34]3[NH:38][N:37]=[N:36][N:35]=3)=[CH:30][C:29](=[O:39])[C:28]=2[CH:27]=[CH:26][CH:25]=1>>[O:39]=[C:29]1[C:28]2[CH:27]=[CH:26][CH:25]=[C:24]([NH:23][C:20]([C:15]3[CH:16]=[C:17]4[C:12](=[CH:13][CH:14]=3)[O:11][CH:10]([CH2:9][CH2:8][CH2:7][C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[CH2:19][CH2:18]4)=[O:22])[C:33]=2[O:32][C:31]([C:34]2[NH:38][N:37]=[N:36][N:35]=2)=[CH:30]1.[CH3:10][OH:11]

Participants

4

Reactant 2

HCID 19606307HCID 19606307, compoundHCID 178507421HCID 178507421, compound

Product 2

HCID 887MethanolYield 65%HCID 178521893HCID 178521893, compound

Procedure

Following the process described in example 2 (point K), starting from 2-(3-phenylpropyl)-6-chromanecarboxylic acid and 8-amino-4-oxo-2-(5-1H-tetrazolyl)-4H-1-benzopyran, the title compound was prepared as a white solid which decomposes at temperatures higher than 370° C. and which was purified by crystallization in methanol (65% yield).

Workup

  1. customdecomposes at temperatures higher than 370° C.

Sources & evidence

ORD record
ord-0f1eddfa76b8474fa2ce1eb7e4d1f5ce
Source dataset
uspto-grants-1999_11
Patent number
US05990142

Reaction notes

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