反应详情

温度

200 °C

A mixture of ethyl 4-allyloxybenzoate (10.0 g, 48.5 mmol) and N,N-dimethylaniline (20 ml) was left under stirring at 200° C. for 48 h, then diluted with ethyl acetate (150 ml) and washed with 1M HCl. After drying and evaporating off the solvent, a crude was obtained which was purified by chromatography through a silica gel column, eluting with n-hexane:ethyl acetate, 95:5, thereby recovering 6.85 g of the title compound (69% yield).

1. waitwas left
2. washwashed with 1M HCl
3. customAfter drying
4. customevaporating off the solvent
5. customa crude was obtained which
6. customwas purified by chromatography through a silica gel column
7. washeluting with n-hexane