反应详情

温度

51 °C

51.45 g(0.43 mmole) of (R)-(+)-α-methylbenzylamine was dissolved in 52 ml of dichloromethane and 63.78 g(0.51 mmole) of 2-bromoethanol was added thereto. This mixture was stirred at 51° C. for 50 hours to complete the reaction. The reaction solution was concentrated under reduced pressure and the residue was subjected to fractional distillation to obtain 54 g of the title compound having pale yellow color.

1. customthe reaction
2. concentrationThe reaction solution was concentrated under reduced pressure
3. distillationthe residue was subjected to fractional distillation