Diethanolamine → 5-Amino-3-acetoxymethyl-N,N-bis(2-hydroxyethyl)-2,4,6-triiodobenzamide

HRID 1604183Notes

Reaction equation

HRID 1604183 reaction equation
[NH2:1][C:2]1[C:3]([I:18])=[C:4]([CH2:13][O:14][C:15](=[O:17])[CH3:16])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7](Cl)=[O:8].[NH:19]([CH2:23][CH2:24][OH:25])[CH2:20][CH2:21][OH:22]>>[NH2:1][C:2]1[C:3]([I:18])=[C:4]([CH2:13][O:14][C:15](=[O:17])[CH3:16])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7]([N:19]([CH2:23][CH2:24][OH:25])[CH2:20][CH2:21][OH:22])=[O:8]

Participants

3

Reactant 2

HCID 8113DiethanolamineHCID 184293385-Amino-3-acetoxymethyl-2,4,6-triiodobenzoyl chloride

Product 1

HCID 184292425-Amino-3-acetoxymethyl-N,N-bis(2-hydroxyethyl)-2,4,6-triiodobenzamide

Procedure

5-Amino-3-acetoxymethyl-2,4,6-triiodobenzoyl chloride was reacted with diethanolamine according to the general procedure in Example 24g. Yield of isolated crude product was 98%.

Workup

  1. customYield of isolated crude product

Sources & evidence

ORD record
ord-cd8ed7f068fd4e26841a62a9efb0ea18
Source dataset
uspto-grants-1999_11
Patent number
US05993780

Reaction notes

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