Thionyl Chloride → HCID 12760482, compound

HRID 1604199Notes

Reaction equation

HRID 1604199 reaction equation
[CH:1]([C:3]1[CH:13]=[CH:12][C:6]([O:7][CH2:8][C:9](O)=[O:10])=[CH:5][CH:4]=1)=O.S(Cl)([Cl:16])=O.[Cl-:18].[Ca+2].[Cl-:20]>>[Cl:18][CH:1]([Cl:16])[C:3]1[CH:13]=[CH:12][C:6]([O:7][CH2:8][C:9]([Cl:20])=[O:10])=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 89177Acetic acid, 2-(4-formylphenoxy)-HCID 5284359Calcium Chloride

Product 1

HCID 12760482HCID 12760482, compound

Procedure

4-Formylphenoxyacetic acid (5 parts) was heated for 90 minutes under reflux with thionyl chloride (25 parts) in a flask fitted with an anhydrous calcium chloride filled drying tube. The resultant red colored solution was evaporated under reduced pressure to give a red colored oil which was distilled at 120° C. and 0.4 mm Hg pressure to yield 4-(dichloromethyl)phenoxyacetyl chloride (1.2 parts).

Workup

  1. additionfilled
  2. customdrying tube
  3. customThe resultant red colored solution was evaporated under reduced pressure
  4. customto give a red colored oil which
  5. distillationwas distilled at 120° C.

Sources & evidence

ORD record
ord-c86181e6616b46d8b4f2ad21a17c3f1d
Source dataset
uspto-grants-1999_11
Patent number
US05994033

Reaction notes

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