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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1604202Generated: October 31, 2026

L-Leucine → Alpha-Cyano-4-Hydroxycinnamic Acid

https://huagongshe.com/reaction/1604202

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-LeucineHCID 6106—
Reactant(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 107526—
ReactantMonobasic potassium phosphateHCID 516951—
ReactantHCID 178419078HCID 178419078—
ProductAlpha-Cyano-4-Hydroxycinnamic AcidHCID 2102—

Reaction Steps

YNB-1 agar: 3.3 g/l KH2PO4, 16.7 g/l agar, pH adjusted to 7. Autoclaved for 20 min. at 121° C. After autoclaving, 25 ml of a 13.6% yeast nitrogen base without amino acids, 25 ml of a 40% glucose solution, 1.5 ml of a 1% L-leucine solution and 1.5 ml of a 1% histidine solution were added per 450 ml agar.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05994113
Source datasetuspto-grants-1999_11
ORD IDord-39f714c8ffba49c881633c2f45c00913
Source noteuspto-grants-1999_11