HCID 54512153, compound → HCID 22008532, compound

HRID 1604316Notes

Reaction equation

HRID 1604316 reaction equation
[CH:1](=[N:8][N:9]([C:21]1[CH:26]=[C:25]([Cl:27])[C:24]([CH2:28][C:29]2[CH:34]=[CH:33][C:32]([Cl:35])=[CH:31][CH:30]=2)=[C:23]([Cl:36])[CH:22]=1)[C:10]([NH:12][CH2:13]C(OCC)OCC)=[O:11])C1C=CC=CC=1>C(#N)C.Cl>[Cl:27][C:25]1[CH:26]=[C:21]([N:9]2[C:10](=[O:11])[NH:12][CH2:13][CH:1]=[N:8]2)[CH:22]=[C:23]([Cl:36])[C:24]=1[CH2:28][C:29]1[CH:34]=[CH:33][C:32]([Cl:35])=[CH:31][CH:30]=1

Participants

4

Reactant 1

HCID 54512153HCID 54512153, compound

Product 1

HCID 22008532HCID 22008532, compoundYield 95%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidCatalystHCID 6342AcetonitrileSolvent

Procedure

In 5 ml of acetonitrile was dissolved 0.4 g of 1-benzylidene-2-[4-(4-chlorobenzyl)-3,5-dichlorophenyl]-4-(2,2-diethoxyethyl)-semicarbazide. To the solution was added one drop of 35% hydrochloric acid. The mixture was stirred for one hour at room temperature. The reaction mixture was cooled, then resulting crystalline precipitate-of the titled compound was collected by filtration. The yield was 95%. m.p. 199-200° C.

Workup

  1. temperatureThe reaction mixture was cooled
  2. filtrationresulting crystalline precipitate-of the titled compound was collected by filtration

Sources & evidence

ORD record
ord-02487ef7e0be4bfd9759ec4cf944230b
Source dataset
uspto-grants-1999_11
Patent number
US05994355

Reaction notes

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