HCID 19602728, compound → 168892-89-5

HRID 1604328Notes

Reaction equation

HRID 1604328 reaction equation
C([N:8]1[CH2:13][CH2:12][CH:11]([O:14][CH2:15][CH:16]2[CH2:21][CH2:20][N:19]([C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[CH2:18][CH2:17]2)[CH2:10][CH2:9]1)C1C=CC=CC=1>CO.[OH-].[OH-].[Pd+2]>[C:25]([O:24][C:22]([N:19]1[CH2:20][CH2:21][CH:16]([CH2:15][O:14][CH:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)[CH2:17][CH2:18]1)=[O:23])([CH3:28])([CH3:26])[CH3:27]

Participants

4

Reactant 1

HCID 19602728HCID 19602728, compound

Product 1

HCID 19602711168892-89-5

Reagents, catalysts & solvents 2

HCID 9942167Palladium hydroxideCatalystHCID 887MethanolSolvent

Procedure

8.04 g (21 mmol) of 1-benzyl-4-[(1-tert-butyloxycarbonylpiperidin-4-yl)methyloxy]piperidine are exhaustively hydrogenated analogously to Example 5 over palladium hydroxide on carbon in methanol.

Sources & evidence

ORD record
ord-9c0ebd0b24474b1eacfac824e44b871d
Source dataset
uspto-grants-1999_11
Patent number
US05994356

Reaction notes

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