Diethyl Ether → HCID 19602609, compound

Participants

Reaction Steps

The title compound was prepared from using a similar method to that of example 18 by treating 6-[N-(5-Chloro-2-cyclobutylmethoxybenzyl)-N-ethylamino]-3-cyanopyridazine (reference example 27) (2.3 g, 6.46 mmol) with sodium hydroxide (2.6 g, 65 mmol) in water (20 ml) and ethanol (100 ml) to give a gum which solidified on trituration with ether (1.15 g, 47%).

Provenance & Evidence