HCID 15887567, compound → Ethyl 4-(2-hydroxyphenoxy)butanoate

HRID 1604404Notes

Reaction equation

HRID 1604404 reaction equation
C([O:8][C:9]1[CH:23]=[CH:22][CH:21]=[CH:20][C:10]=1[O:11][CH2:12][CH2:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])C1C=CC=CC=1.[H][H]>C(O)(=O)C.[Pd].C(O)C>[OH:8][C:9]1[CH:23]=[CH:22][CH:21]=[CH:20][C:10]=1[O:11][CH2:12][CH2:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16]

Participants

6

Reactant 2

HCID 15887567HCID 15887567, compoundHCID 178418361HCID 178418361, compound2×

Product 1

HCID 15887568Ethyl 4-(2-hydroxyphenoxy)butanoate

Reagents, catalysts & solvents 3

HCID 176Acetic AcidCatalystHCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of (3) (1.57 g, 5.0 mM), ethanol (50 mL), glacial acetic acid (7 drops) and 10% palladium on carbon (0.7 g) was reacted in a hydrogen atmosphere (40 p.s.i.) at room temperature until hydrogen uptake ceased. Concentration of the filtered mixture yielded the product (4) as an oil.

Sources & evidence

ORD record
ord-b113687707d1434e8257e6643a54ff55
Source dataset
uspto-grants-1999_11
Patent number
US05994362

Reaction notes

Loading…