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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 160462Generated: October 25, 2026

Dichloromethane → 5-bromo-3-(2-trifluoromethoxy-phenyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridine

https://huagongshe.com/reaction/160462

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
Reactant2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)HCID 2777204—
Reactant5-bromo-3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazolo[3,4-b]pyridineHCID 59836134—
Product5-bromo-3-(2-trifluoromethoxy-phenyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridineHCID 57975821—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-2d1c41415fb14a908c49f5675cc2e9d0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)