HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl (E)-3-[2-(4-tert-butylthiazol-2-yl)benzofuran-5-yl]propenoate → Ethyl 3-[2-(4-tert-butylthiazol-2-yl)benzofuran-5-yl]propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl (E)-3-[2-(4-tert-butylthiazol-2-yl)benzofuran-5-yl]propenoate | HCID 86754881 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ethyl 3-[2-(4-tert-butylthiazol-2-yl)benzofuran-5-yl]propionate | HCID 19603662 | 99.4% |
Reaction Steps
A solution of ethyl (E)-3-[2-(4-tert-butylthiazol-2-yl)-benzofuran-5-yl-]propenoate (0.65 g) in tetrahydrofuran (10 ml) was hydrogenated over 10% Pd--C (0.1 g) at room temperature under atmospheric pressure. After removal of the catalyst by filtration the filtrate was concentrated under reduced pressure to give ethyl 3-[2-(4-tert-butylthiazol-2-yl)benzofuran-5-yl]propionate (0.65 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05994378 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-bbfc218121b8439385134455d9d025d2 |
| Source note | uspto-grants-1999_11 |