HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 19603751, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Thioacetamide | HCID 2723949 | — |
| Reactant | HCID 19603837 | HCID 19603837 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 19603751 | HCID 19603751 | — |
Reaction Steps
A mixture of 4-tert-butyl-2-[5-(cyanomethyl)benzofuran-2-yl]thiazole (1.31 g) and thioacetamide in a mixture of 4N-hydrogen chloride of 1,4-dioxane (4 ml) and chloroform was stirred under reflux for 30 minutes and removed the solvent at the same temperature. The residue was washed with water to give crude 4-tert-butyl-2-[5-(thiocarbamoylmethyl)-benzofuran-2-yl]thiazole (1.23 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05994378 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-69ee25559fc64d9c8336fff485e37bec |
| Source note | uspto-grants-1999_11 |