Hydrogen Bromide → 5-Amino-2-chlorophenol

HRID 1604856Notes

Reaction equation

HRID 1604856 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[CH:4][C:3]=1[O:9]C.Br>C(O)(=O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[CH:4][C:3]=1[OH:9]

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 131036924-Chloro-3-methoxyaniline

Product 1

HCID 806765-Amino-2-chlorophenol

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

4.35 Moles (688 grams) of 2-chloro-5-amino anisole are introduced into 3.44 liters of hydrobromic acid (d = 1.49) to which has been added 1.38 liters of acetic acid.

Sources & evidence

ORD record
ord-7b4cdde4374848dd96b836049650a419
Source dataset
uspto-grants-1976_04
Patent number
US03948596

Reaction notes

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