反应详情

温度

70 °C

0.05 Mole (7.17 grams) of 2-chloro-5-aminophenol is dissolved in 21 cc of dioxane at 75°C. There is then added, with agitation, 0.05 mole (5.1 grams) of acetic anhydride. At the end of this addition, the reaction medium is maintained for 10 minutes at 70°C and then cooled. The raw product which has crystallized in then filtered and recrystallized in a hydroalcoholic medium. It exhibits a melting point of 212°C.

1. additionAt the end of this addition
2. temperaturecooled
3. customThe raw product which has crystallized
4. filtrationin then filtered
5. customrecrystallized in a hydroalcoholic medium