反应详情

To a stirred solution of 1.15 moles of amylmagnesium bromide in 335 ml. anhydrous tetrahydrofuran at -8° is added 0.028 moles of lithium chlorocyanocuprate in tetrahydrofuran, prepared in Example 1 above. Dropwise addition of 1.00 moles of Z-9-octadecenyl bromide is carried out with cooling to maintain the temperature at from about -6° to +5°. The reaction mixture is maintained at -5° to +5° for 1 hour. Magnesium bromide is precipitated by the addition of hexane and a minor amount of water. The slurry of granular solid is filtered and washed with hexane. Evaporation of solvent from the filtrate gives a clear amber oil of Z-9-tricosene in 99% yield.

1. customprepared in Example 1 above
2. temperaturewith cooling
3. temperatureto maintain the temperature at from about -6° to +5°
4. temperatureThe reaction mixture is maintained at -5° to +5° for 1 hour
5. customMagnesium bromide is precipitated by the addition of hexane
6. filtrationThe slurry of granular solid is filtered
7. washwashed with hexane
8. customEvaporation of solvent from the filtrate