Ammonium Hydroxide → HCID 21548226, compound

HRID 1604977Notes

Reaction equation

HRID 1604977 reaction equation
C[O:2][C:3]([C:5]1[NH:6][C:7](=[O:10])[S:8][CH:9]=1)=O.[OH-].[NH4+:12]>>[NH2:12][C:3]([C:5]1[NH:6][C:7](=[O:10])[S:8][CH:9]=1)=[O:2]

Participants

3

Reactant 2

HCID 14923Ammonium HydroxideHCID 108774012-Hydroxy-thiazole-5-carboxylic acid methyl ester

Product 1

HCID 21548226HCID 21548226, compound

Procedure

48 g of 4-methoxycarbonyl-4-thiazoline-2-one were added to 600 ml of concentrated aqueous ammonium hydroxide and the mixture was stirred for 24 hours. The mixture was acidified and filtered to obtain 30 g of 4-aminocarbonyl-4-thiazoline-2-one in the form of white crystals melting at 261°C.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-325783dce29649dcb7186d199a40324c
Source dataset
uspto-grants-1976_04
Patent number
US03948925

Reaction notes

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