Sodium Hydroxide → HCID 21548938, compound

Participants

Reaction Steps

A solution of 2.54 g. of 2-(2-xanthenyl)-propionic acid in 20 ml. of absolute THF is added dropwise to a mixture of 0.57 g. of LiAlH4 in 20 ml. of absolute THF. The mixture is refluxed for 8 hours, 2 ml. of water in 3 ml. of THF, as well as 4 ml. of 25% sodium hydroxide solution are added thereto, the mixture is decanted and the residue washed with ether. After the drying, filtration, and evaporation of the combined organic phases, 2-(2-xanthenyl)-propanol is obtained, m.p. 86°-89°.

Provenance & Evidence